When a baby is diagnosed with Necrotizing Entercolitis there are only two types of surgeries available, both are invasive, expensive and have lower than medically acceptable success rates. If the patient survives infection and liver damage, they may be left with a colostomy bag or continuous need for anti-rejection medications.
Dr. Grikscheit and the Keck School of Medicine at the Childrens Hospital of Los Angeles are working on an engineered intestine which will be stronger than the current graft solution. Dr. Grikscheit and team have proven success in engineering stronger and thicker intestines with laboratory rats and foresee their work will not only save the lives of many babies suffering from necrotizing enterocolitis but also aid in future treatments of trauma, vascular accidents, gastrointestinal cancer resection. Learn more about this innovative new treatment here.
The bicycling industry has experienced a boom of innovation in just the last 5 years, and the Leardon Solutions Team is proud to be a part of helping entrepreneurs create products that are safe, stylish and useful for the bicycling masses. Here’s our list of the top 5 bike gadgets that every cyclist should have in their arsenal.
Finally, a device that captures all of your hard bicycling power and puts it into charging your small devices! For a mere $99, you’ll have the power to charge all of our devices right at the tip of your toes. Lean more about the Atom here.
Traditionally bikers have always relied on small front and back lights to warn cars of their presence during the evening and nighttime hours. Today bikers have a much better solution with Revolights, a revolutionary lighting system that enhances a bike riders visibility with bright red (for the rear) and white (for the front) lights reflected onto the front and back of tires. The Revolights can be seen from 360 degrees,which means for the first time cars coming from all directions will be able to see bike riders at night. Buy your set of Revolights here.
The stylish and safe Torch Helmet is a product that is near and dear to our hearts as we worked with the creators of the Torch helmet to make an elegant manufacturing prototype. Much like the Revolight, the Torch Helmet aims to up visibility in all directions by using bright white and red lights, but the Torch utilizes something that most all bicyclists wear – Helmets! Not only does the Torch Helmet help cars see you from multiple angles but it also helps light your path. We find that the design is as beautiful at night as it is in the day. Sign up for the Torch mailing list and be one of the first to know when the helmet and other Torch apparel will available for purchase. You can also follow their progress on Facebook here.
Now that we’re firmly on the subject of illumination, why not add Zackees Turn Signal Gloves to you list of bicycle accessories? With Zackees the power of lighted turn signals will be just a hand squeeze away. Before you get too excited we must say that Zackees are not on sale just yet. We recommend you Sign up to be notified about the Zackees Turn Signal Gloves and be one of the first to back their soon to be launched Kickstarter campaign.
At first glance, the invisible bike helmet seems to be a hoax, but alas it is a true – you can wear a bike helmet and look fashionable at the same time. We have to give it to the two Swedish entrepreneurs who were passionate enough to take their idea to market in only 8 years time. You won’t believe the innovation until you see it in action.
The Invisible Bicycle Helmet | Fredrik Gertten from Focus Forward Films on Vimeo.
Right now only Europeans can snatch up an inflatable helmet for $500. Only time will tell if high fashion bicycle accessories will pay off. We sure hope they do!
Achieving optimal manufacturing efficiency is paramount for every company trying to produce a product. While the concept of lowering manufacturing costs to increase profit margins sounds simple – it comes with quite a few complications that only experienced teams can help mitigate. Here’s some of the factors that are needed to achieve optimal manufacturing efficiency.
Design for Manufacturing
It’s always important to start off on the right foot with a design that is not only perfect for your application but is also manufacturable. If you are just starting out, we suggest choosing a firm that holds design for manufacturing high on their list. If you find yourself in the unfortunate position of working with a design that was not optimized for manufacturing, it’s time to switch gears and re-design or work through the kinks in the manufacturing process that are holding you back.
Relationships with Suppliers.
Some people assume that a relationship with a factory is the same as a relationship with a supplier. Unfortunately, this is not the case. Factories do indeed have relationships with certain suppliers, but those relationships may not serve you or your product well. To gain an edge and ultimately reduce the cost of your product and improve the quality, it’s important to have a team that has existing relationships with various suppliers.
Relationships with Factories
Relationships with factories can mean the difference between an on time under budget product or a late, expensive pair of shackles. As you know, relationships do not grow overnight nor can they be ignored for months while you work on other aspects of your business. Working with a team like Leardon Solutions means you don’t have to worry about the intricacies of relationship building in the manufacturing world and can focus your time on building your business.
Solid Program/Project Management
The success of every product in the manufacturing process hinges on a variety of complex decisions being made in a particular order and on time. Without proper checkpoints and gates the manufacturing process can fall apart. Your product development team will need to stay on track and on budget.
In order to achieve optimal manufacturing efficiency you must either possess all of the above skills or have a team with a proven track record that does.Contact usto learn more about how we can optimize your manufacturing process.
This headline comes as no surprise to us here at Leardon Solutions. For the past 8 years we have proudly offered local and global small to medium sized businesses industrial design, prototyping and manufacturing services within action sports, medical device and diagnostics, and consumer electronics industries to name a few.
Without a doubt, San Diego has some great innovation going on and a slew of support programs to help small and medium sized businesses.
Here is a great list of San Diego and Southern California incubators and resources to reference should your venture seek assistance.
Preeclampsia affects 5-8% of pregnancies, approximately 300,000 women in the United States every year. It is a leading cause of maternal and infant illness and death, and premature birth.
Preeclampsia, diagnosed as early as the 20th week of pregnancy, is characterized by high blood pressure (hypertension), swelling from fluid retention (edema), and protein in the urine (proteinuria). Other common symptoms include headaches, dizziness, and blurred vision. Preeclampsia can be life-threatening to both the mother and the developing baby. Left untreated, preeclampsia could lead to several serious side effects, including HELLP syndrome, eclampsia, and death.
Advanced Prenatal Therapeutics, Inc. is working with Leardon Solutions to develop a Targeted Apheresis Cartridge for Preeclampsia (TAC- PE) which will be used in apheresis machines to remove the harmful sFlt-1 proteins, associated with causing preeclampsia, from the blood of pregnant mothers. APT’s targeted apheresis could lead to prolonged pregnancy enabling healthy fetus development and help mothers and babies survive. APT’s targeted apheresis method can become the standard of care for treating preeclampsia.
Learn howLeardon Solutions can help you design, prototype and manufacture your medical device today.
The Innovation in Pediatrics (CTIP) consortium created by Children’s Hospital Los Angelesand the University of Southern California (USC) were recently awarded a 1.5 million dollar grant by the FDA. Leardon Solutions is a proud partner of the consortium and contributor to the FDA grant proposal – providing them with top notch engineering, design, prototyping, and manufacturing services.
Today we’re recognizing the 3d printer innovations that are rocking the science, medical, business, product development and design worlds.
In the Summer of 2014 NASA is planning to launch their very first 3d printer into space which will give astronauts the ability to create useful and necessary hardware pieces on the spot. If that’s not enough of a Star Trek parallel, it has also been rumored that NASA is also in the works to create a 3d printer which can create food on demand in space. Since innovators have already created chocolate dispensing 3d printers, we’re pretty confident that eating 3d pizza in space is not far behind.
Although mostly a novelty – artists, makers, and geeks give a standing ovation to the 3d doodler which allows for free form 3d printing in various colors. Proof is in the Kickstarter funding – of just over 2.3 million dollars.
3d Printing in Medicine
Biotech companies are always on the bleeding edge (no pun intended?) which means before you know it our hospitals will be creating organs, tissue and body parts on a 3d printer.
Although “Bioprinting” is in early stages, it’s making significant strides, having already printed prototype kidneys, skin graphs, ears, bones and more. Read the in depth Popular Science article of the rise of bioprinting here.
At Home 3d Printers
ROBO 3d is one of the first to create a smaller and more budget friendly 3d printer which can be enjoyed by designers, engineers and hobbyists alike. This new affordable 3d printer is sure to create a boom in many different industries. In fact, we predict that the constant innovation and accessibility to 3d printers will lead to a demand for 3d printers in every household. Combine that with NASA’s food printer and we are not far away from living like the Jetsons.
Surgical procedures have come a very long way over the last decade. The technologies and techniques for treating acute cancers and other types of ailments have progressed by an order of magnitude. However, procedures which require repetitive entry into the bones, have mostly gone unchanged, and as a result can cause a variety of life-threatening infections and complications in patients. Sure, Antibiotics can fix a lot, but there is a new string of medical devices being developed to help reduce the chance of infection or assist with the treatment of infection.
Infections can be very problematic in that they are difficult to treat, often requiring additional surgeries to access the source of the problem. In some instances, bones must be re-drilled to access the infected area. These problems become compounded when addressing this issue within children.
A Proposed Solution:
Enter the Temporary Bone Filler, an innovative medical device being that is currently being developed by Children’s Hospital of Los Angeles with assistance from Leardon Solutions.
The Temporary Bone Filler is a plug that is placed in an open surgical cavity allowing easier access to that cavity at a later time with minimally invasive techniques. The Bone Filler prevents the bone from growing over the surgical site and sealing the hole before treatment is complete. A process that can take from 6 weeks to 6 months depending on conditions and the location of the cavity.
Areas of Application:
Spinal fusion surgery and other non-spine applications
Implant site infection, implant rejection, necessity of removing implants due to untoward sequlae (spine implants that led to paralysis), poor soft-tissue healing over implants, etc
Leardon Solutions works with leading biotech, life science and medical device clients, and we know that a large part of creating innovative medical devices is to learn from the simple medical devices that changed the world. Here’s four of our favorites!
The Band-Aid Brand Bandage
Earle Dickson inventor of the Band-Aid is proof that solving a seemingly small problem can change the future of infections. It’s good to note that his invention was not globally hailed until Johnson and Johnson created the machinery to mass produce the Band Aid in 1924.
The first thermometers can be traced back to the late 1500′s with a crude measuring instrument created by Galileo. Throughout the centuries the thermometer was refined by a succession of inventors. After a few battles between Celsius and Fahrenheit, the medical world eventually received their first medical thermometer in the late 1800′s, from Sir Thomas Allbutt. Today our homes and hospitals heavily rely on this seemingly simple invention which would not exist without hundreds of years worth of innovation.
The first hypodermic needle was created and used in the late 19th century for administering local anesthesia. However, the largest changes to the hypodermic needle occurred during times of war. WWII gave troops partially disposable syringes for the administration of morphine and penicillin on the battlefield. The Korean War created the need for disposable sterile needles for collecting blood. Finally, by the 1950′s our focus on the needle shifted to a sterile fully disposable needle and plastic syringe.
We have seen significant advancements in medical diagnostic tools thanks to Wilhelm Conrad Röntgen’s accidental discovery of the X-Ray in 1895. Thus proving that the simple act of tinkering can change the world.
We want to know what medical devices you can think of that are simple solutions to big problems.
Don’t miss your opportunity to mingle with the BodyFly Fitness team and try out the revolutionary BodyFly Fitness system yourself! San Diego Charger Ryan Matthews and his BodyFly co-founders will be demonstrating the most innovative new fitness product to hit the market at the Shock Fitness Mezzanine on August 31st between 11 and 2pm.
Click here for more information about the BodyFly Fitness system and how its’ inventors used the experience of the Leardon team to make their dreams become a reality. We look forward to seeing you at the event on Saturday!